Basic Medicine
Roohallah Yousefi; Shahla Mokaramian
Abstract
The coronavirus pandemic, caused by the SARS-CoV-2 virus, has emerged as a significant global threat to all countries and societies. Analyzing infection rates, mortality due to Covid-19, and the impact of vaccination, weather conditions, and demographic and ethnic composition on infection and mortality ...
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The coronavirus pandemic, caused by the SARS-CoV-2 virus, has emerged as a significant global threat to all countries and societies. Analyzing infection rates, mortality due to Covid-19, and the impact of vaccination, weather conditions, and demographic and ethnic composition on infection and mortality rates can provide crucial insights into this disease. SARS-CoV-2, the novel coronavirus causing acute respiratory syndrome, first emerged as a global pandemic in the Chinese city of Wuhan in December 2019. According to the World Health Organization (WHO), there have been 768,237,788 confirmed cases of Covid-19 reported worldwide, resulting in 6,951,677 fatalities as of July 19, 2023. Analyzing various factors like infection rates, mortality, vaccination, weather conditions, and demographics helps us understand the disease better. The United States has the highest COVID-19 death toll, while African countries have reported the lowest. However, Africa's high death-to-infection ratio might be due to inadequate healthcare services and vaccination rates, which require urgent attention. In addition, the relationship between environmental temperatures and COVID-19 cases and mortality is still under investigation.
Basic Medicine
Mehrdad Zamani Esfahlani; Mohammad Irajian
Abstract
Introduction: The available literature offers valuable insights into various aspects of osteomyelitis and its management, but a dedicated investigation into its impact on mortality within the specific context of ICU admissions is warranted. This study aims to fill this knowledge gap, shedding light on ...
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Introduction: The available literature offers valuable insights into various aspects of osteomyelitis and its management, but a dedicated investigation into its impact on mortality within the specific context of ICU admissions is warranted. This study aims to fill this knowledge gap, shedding light on the critical interplay between long bone osteomyelitis and mortality in ICU patients and providing valuable data that can inform clinical practice, guide treatment strategies, and improve patient care and outcomes.Material and Methods: Identification of eligible patients using electronic medical records. Data collection, including demographic information, comorbidities, ICU admission details, microbiological findings, and mortality outcomes. Comparison of the osteomyelitis group and control group with respect to mortality rates during their ICU stay. Subgroup analysis within the osteomyelitis group to explore factors associated with increased mortality.Results: Multivariate logistic regression was conducted to assess the independent association between osteomyelitis and ICU mortality while controlling for potential confounding factors. After adjusting for age, sex, and comorbidities, the odds ratio (OR) for ICU mortality in patients with osteomyelitis was 2.12 (95% confidence interval [CI], 1.11 to 3.89). Notably, this analysis did not reveal a statistically significant association between osteomyelitis and ICU mortality (p =0.125).Conclusion: Our study demonstrates a significant association between osteomyelitis of long bones and increased mortality in patients admitted to the ICU. Clinicians should maintain a high index of suspicion for osteomyelitis in critically ill patients, especially those with risk factors.
