Clinical Medicine
Ali Reza Nasseri; Farshad Mahdavi
Abstract
Introduction: Breast cancer is known as the most common cancer in women and various aspects of dealing with this disease have been studied by researchers for many years. One of these areas is tumor markers and its effect on determining the prognosis of patients and determining the most appropriate treatment ...
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Introduction: Breast cancer is known as the most common cancer in women and various aspects of dealing with this disease have been studied by researchers for many years. One of these areas is tumor markers and its effect on determining the prognosis of patients and determining the most appropriate treatment method. Therefore, we decided to conduct a study to evaluate tumor markers of breast cancer in women candidates for mastectomy.Methods: The clinical records of 100 patients with breast cancer were evaluated for information such as information about pathological examinations of the sample (markers: ER, PR, HER2, P53, CEA) and recurrence of symptoms during a two-year period. Data were analyzed using SPSS ver17 statistical software, descriptive statistics and logistic regression test.Results: 24% had recurrence among which P53 and CEA markers had the highest frequency and in the absence of recurrence group ER and CEA markers had the highest frequency.Conclusion: According to the results of this study, it seems that paying attention to tumor levels of markers such as P53 and CEA can be helpful in identifying people who will have recurrence and attention to it can greatly determine the fate of the disease.
Clinical Medicine
Reza Eghdam Zamiri; Farshad Mahdavi
Abstract
Because long-term drainage can cause problems such as limited mobility of the affected limb and pain in the patient's armpit, studies that can determine the effect of prolonged drainage on serum incidence may lead to earlier drainage. And the reduction of the resulting complications should be helpful. ...
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Because long-term drainage can cause problems such as limited mobility of the affected limb and pain in the patient's armpit, studies that can determine the effect of prolonged drainage on serum incidence may lead to earlier drainage. And the reduction of the resulting complications should be helpful. Therefore, the present study was performed with the aim of the effect of surgical drainage on seroma incidence in breast cancer surgery. This descriptive cross-sectional study was performed during the years 2018 to 2020 with the participation of 152 patients after breast surgery in the hospitals of Tabriz University of Medical Sciences. Diagnosis of seroma after surgery (for one week) was made by a physician and the factors affecting its formation were collected in the data collection form. Data were compared by Chi-square test. The mean age of the study participants was 46 years; Tumor size in most participants was less than two centimeters; The stage of the disease was in the majority of participants I, II and in most of them the breast mass was completely removed. The surgical drain remained in the majority of participants for 5 to 9 days. The prevalence of seroma in this study was 35%; The results of this study showed that the type of surgical device, the number of days of drain use, as well as the stage of the disease and the type of surgery performed on the breast have no role in the incidence of seroma.
