Original Research Article
Clinical Medicine
Maryam Milani Fard; Amir Mohammad Milani Fard
Abstract
In this study, a controlled drug delivery system was modeled to release the drug dissolved in a polymer matrix by polymer degradation. This system is in the form of a page. The drug is released into the environment by the mechanism of penetration and degradation of the polymer. What comes to mind when ...
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In this study, a controlled drug delivery system was modeled to release the drug dissolved in a polymer matrix by polymer degradation. This system is in the form of a page. The drug is released into the environment by the mechanism of penetration and degradation of the polymer. What comes to mind when you first hear the name of the drug may be nothing more than pills, capsules or ampoules! While the world of medicine and the methods of its delivery to the body are not limited to these. Drugs usually enter the body in both digestive and non-digestive ways. The introduction of drugs from these methods has problems and limitations, and for this reason, researchers were looking for ways that could solve the above problems to a large extent. Following these efforts, controlled drug delivery systems were introduced, which have many benefits. The most important of these advantages include the ability to maintain the drug concentration at a relatively constant level for a certain period of time, the ability to adjust the drug release rate depending on the drug delivery site, the ability to deliver the drug to a specific organ or tissue, the ability to deliver multiple drugs with one formulation. These systems have revolutionized the treatment of many diseases and are evolving.
Review Article
Clinical Medicine
Maryam Milani Fard; Amir Mohammad Milani Fard
Abstract
Due to the diversity of polymers as well as their complex behavior, research in this field is still widely developed. Because biodegradable polymers become decomposed in the human body after decomposition, they are more commonly used because surgery is not required to remove these polymers from the body ...
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Due to the diversity of polymers as well as their complex behavior, research in this field is still widely developed. Because biodegradable polymers become decomposed in the human body after decomposition, they are more commonly used because surgery is not required to remove these polymers from the body after the drug is released. Understanding the mechanism, modeling and studies of drug release from homopolymers, copolymers and mixtures of this family of polyesters is the focus of this research. In this research, the release of drug from homo and biodegradable copolymer in pure form with drug and finally the mixture of the two with drug has been investigated to determine the differences. In the proposed model, the equations that represent the degradation of the polymer are used to be able to predict the degradation of the polymer. The drug used is paclitaxel, which is a very important drug for chemotherapy. Since this drug is administered every 3 weeks for 3 hours, it is necessary to use controlled systems. Therefore, the purpose of this study is to achieve a predictable model for controlled release of paclitaxel, so that this model responds to the release of paclitaxel at any time.
Original Research Article
Chemistry
Nabil Vaeli
Abstract
In this study, Carvacrol or Cymophenol as a combination, as the number of reports of antibiotic-resistant pathogenic microorganisms increases and considering that plant-derived products can potentially treat microbial growth in different conditions and in specific cases of the disease. Very strong anti-cancer ...
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In this study, Carvacrol or Cymophenol as a combination, as the number of reports of antibiotic-resistant pathogenic microorganisms increases and considering that plant-derived products can potentially treat microbial growth in different conditions and in specific cases of the disease. Very strong anti-cancer and also an antibacterial treatment of yeast infections from Oliveria decumbens plant by supercritical fluid CO2 with the help of ultrasound at 150,180,210 bar and temperatures of 55, 45 and 65 ° C. The compounds were examined by GC / MS device. The method is about 37% more than the distillation method with Clevenger apparatus. Also, to increase the extraction rate, C65 temperature, 180 bar pressure and 37 kHz frequency were determined as optimal conditions, in which about 26% compared to the case without ultrasound without extraction.
Review Article
Engineering
Mohammad Ranjbarian
Abstract
The model of excellence of the organization is the most extensive tool of self-evaluation in the world and is the basis for designing national awards in various countries, including Iran. Numerous studies have shown that the use of management evaluation models such as excellence model has a positive ...
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The model of excellence of the organization is the most extensive tool of self-evaluation in the world and is the basis for designing national awards in various countries, including Iran. Numerous studies have shown that the use of management evaluation models such as excellence model has a positive effect on the performance of organizations. Since organizations must continuously evaluate their performance and formulate their future strategies based on these evaluations, among the many models designed to evaluate performance in this study, the indicators of the organizational excellence evaluation model Used to measure and evaluate the performance of the organization. The EFQM model was introduced in 1991 as a business excellence model that provided a framework for organizational judgment and self-evaluation and ultimately European quality reward, which was implemented in 1992. This model demonstrates the sustainability benefits that a superior organization must achieve. This model quickly attracted the attention of European companies and it was found that public sector organizations and small industries are also interested in using it. Found worldwide.
Original Research Article
Engineering
Seyed Aliakbar Saadpour
Abstract
The genus Saprolegnia is one of the most important pathogenic aquatic fungi in farmed and wild fish. In this paper, 100 samples were prepared from 10 fish ponds in Sari, Neka and Behshahr. After cultivation, purification and macroscopic and microscopic examinations, we were able to isolate the fungi ...
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The genus Saprolegnia is one of the most important pathogenic aquatic fungi in farmed and wild fish. In this paper, 100 samples were prepared from 10 fish ponds in Sari, Neka and Behshahr. After cultivation, purification and macroscopic and microscopic examinations, we were able to isolate the fungi Saprolegnia parasitka, Saprolegnia and Aclia. Their prevalence was 48% Parasitica, 38% Saprolegnia, 36% Aclias and 15% other fungi, respectively. Their frequencies are 48 Parasitica, 38 Saprolegnia, 36 Aclias and 15 other fungi, respectively. Also, in the study of other parameters and their effect on the presence of Saprolegnia, it was observed that the ambient temperature of the water was suitable for the growth of this fungus and also the pH and salinity of the water also affected the presence of Saprolegnia.
Original Research Article
Mohammad Ranjbarian
Abstract
Continuous improvement of organizational performance creates a huge synergistic force that can support the growth and development program and create opportunities for evaluating organizational excellence. Governments, organizations and institutions are making progressive efforts in this regard. Without ...
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Continuous improvement of organizational performance creates a huge synergistic force that can support the growth and development program and create opportunities for evaluating organizational excellence. Governments, organizations and institutions are making progressive efforts in this regard. Without reviewing and gaining knowledge of the progress and achievement of goals and without identifying the challenges facing the organization and obtaining feedback and information on the implementation of policies and identifying issues that need serious improvement, continuous performance improvement will not be possible. All of the above is not possible without measurement and evaluation. The European Quality Award has left a mark on the competitiveness of European companies and organizations, and the widespread use of these models in other countries is undoubtedly the reason for the amazing effectiveness and impact of these models. In this article, the definitions and theoretical foundations of performance evaluation of excellence have been studied in a completely scientific way.
Original Research Article
Psycology
Hosna Karimi; Rezvaneh Namazi Yousefi; Mahjoubeh Zanganeh Gheshlaghi; Esmail Bana; Fatemeh Moslemnezhad
Abstract
Objective: The aim of this study was to compare the quality of life, meaning of life, body image and mental health in two groups of postmenopausal and non-menopausal women with emphasis on their education. Methods: The statistical population included all postmenopausal and non-menopausal women. The statistical ...
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Objective: The aim of this study was to compare the quality of life, meaning of life, body image and mental health in two groups of postmenopausal and non-menopausal women with emphasis on their education. Methods: The statistical population included all postmenopausal and non-menopausal women. The statistical sample included 50 people, of whom 25 were postmenopausal and 25 were non-menopausal, who were selected through women's gatherings from among women who wanted to participate in the study. The General Health Questionnaire (GHQ-28), the Women's Quality of Life Questionnaire, the 12-item Stieger and fraser meaning of life questionnaire, the Physical Self-Description Questionnaire, and demographic characteristics were used. Data were analyzed by independent t-test and two-factor analysis of variance. Findings: indicate a significant difference between quality of life in postmenopausal and non-postmenopausal women with a diploma level, which means that the quality of life in non-postmenopausal women with a diploma is better than the quality of life in postmenopausal women with the same level of education. But the quality of life in women was not different from the level of primary and university education in these two groups (postmenopausal and non-menopausal women), so the higher the level of education of women, the better their quality of life. In this study, physical image, meaning of life and mental health were the same between postmenopausal and non-menopausal women and there was no significant difference, but the higher the level of education of both groups of women, the more desirable physical image and higher mental health.
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