Three-Component Synthesis of Bis(indolyl)methane with Sulfanilic Acid as an Efficient Catalyst

Banari, Hoda; Kiyani, Hamzeh; Pourali, Alireza; Hajiabbastabar Amiri, Parvin

doi:10.48309/ejst.2024.444677.1133

Articles in Press

Document Type : Original Research Article

Authors

¹ Department of Chemistry, Damghan University, Damghan, Semnan, Iran

² Department of Chemistry, Faculty of Science, Shahrekord University, Shahrekord, Iran

https://doi.org/10.48309/ejst.2024.444677.1133

Abstract

The biological activities and therapeutic qualities of indoles as well as their derivatives have garnered significant attention. I n this study, the solid acidic organocatalyst (sulfanilic acid) was examined for the synthesis of derivatives of bis(indolyl)methanes (BIMs) at ambient temperature and in water and ethanol as solvent. BIMs was prepared and characterized by appearance, TLC, FT-IR, and melting point and were further supported by CHNS analysis. The approach has a lot of advantages, including a clean reaction, operational simplicity, a simple experimental work-up process, waste minimization, non-toxicity, quicker reaction times, and high yields of the compounds.

Keywords

Main Subjects

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Eurasian Journal of Science and Technology

Three-Component Synthesis of Bis(indolyl)methane with Sulfanilic Acid as an Efficient Catalyst

References

References

Articles in Press, Accepted Manuscript
Available Online from 12 May 2024

Three-Component Synthesis of Bis(indolyl)methane with Sulfanilic Acid as an Efficient Catalyst

References

References

Articles in Press, Accepted Manuscript Available Online from 12 May 2024

Articles in Press, Accepted Manuscript
Available Online from 12 May 2024